3SJH

Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP-Latrunculin A

3SJH の概要

• エントリーDOI: 10.2210/pdb3sjh/pdb
• 分子名称: Actin, alpha skeletal muscle, Ciboulot/Thymosin beta-4 chimeric protein, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: protein-protein complex, contractile protein, protein binding
• 由来する生物種: Drosophila melanogaster; 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton: P68135 P62326
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48804.33

構造登録者

Renault, L.,Husson, C.,Carlier, M.F.,Didry, D. (登録日: 2011-06-21, 公開日: 2012-01-25, 最終更新日: 2023-09-13)

• 主引用文献: Didry, D.,Cantrelle, F.X.,Husson, C.,Roblin, P.,Moorthy, A.M.,Perez, J.,Le Clainche, C.,Hertzog, M.,Guittet, E.,Carlier, M.F.,van Heijenoort, C.,Renault, L.; How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly; Embo J., 31:1000-1013, 2012; PubMed: 22193718; DOI: 10.1038/emboj.2011.461

実験手法

X-RAY DIFFRACTION (1.75 Å)