3SGX
Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1100
Summary for 3SGX
| Entry DOI | 10.2210/pdb3sgx/pdb |
| Related | 3SGT 3SGV 3SH0 |
| Descriptor | Undecaprenyl pyrophosphate synthase, 4-{3-[(biphenyl-4-ylcarbonyl)amino]phenoxy}benzene-1,2-dicarboxylic acid (3 entities in total) |
| Functional Keywords | alpha/beta, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Escherichia coli |
| Total number of polymer chains | 2 |
| Total formula weight | 57869.14 |
| Authors | Cao, R.,Liu, Y.-L.,Oldfield, E. (deposition date: 2011-06-15, release date: 2012-12-19, Last modification date: 2023-09-13) |
| Primary citation | Zhu, W.,Zhang, Y.,Sinko, W.,Hensler, M.E.,Olson, J.,Molohon, K.J.,Lindert, S.,Cao, R.,Li, K.,Wang, K.,Wang, Y.,Liu, Y.L.,Sankovsky, A.,de Oliveira, C.A.,Mitchell, D.A.,Nizet, V.,McCammon, J.A.,Oldfield, E. Antibacterial drug leads targeting isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 110:123-128, 2013 Cited by PubMed: 23248302DOI: 10.1073/pnas.1219899110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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