3SGV

Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1290

Summary for 3SGV

• Entry DOI: 10.2210/pdb3sgv/pdb
• Related: 3SGT 3SGX 3SH0
• Descriptor: Undecaprenyl pyrophosphate synthase, 2-{[3-(3,4-dimethylphenoxy)phenyl]carbamoyl}-4-nitrobenzoic acid (3 entities in total)
• Functional Keywords: alpha/beta, transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 58994.19

Authors

Cao, R.,Liu, Y.-L.,Oldfield, E. (deposition date: 2011-06-15, release date: 2012-12-19, Last modification date: 2024-02-28)

• Primary citation: Zhu, W.,Zhang, Y.,Sinko, W.,Hensler, M.E.,Olson, J.,Molohon, K.J.,Lindert, S.,Cao, R.,Li, K.,Wang, K.,Wang, Y.,Liu, Y.L.,Sankovsky, A.,de Oliveira, C.A.,Mitchell, D.A.,Nizet, V.,McCammon, J.A.,Oldfield, E.; Antibacterial drug leads targeting isoprenoid biosynthesis.; Proc.Natl.Acad.Sci.USA, 110:123-128, 2013; PubMed: 23248302; DOI: 10.1073/pnas.1219899110

Experimental method

X-RAY DIFFRACTION (1.61 Å)