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3SGP

Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L

Summary for 3SGP
Entry DOI10.2210/pdb3sgp/pdb
Related3SGM 3SGN 3SGO 3SGR 3SGS
DescriptorAlpha-crystallin B chain, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywordsamyloid, amyloid oligomer, beta cylindrin, protein fibril
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P02511
Total number of polymer chains4
Total formula weight5212.50
Authors
Laganowsky, A.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2011-06-15, release date: 2012-03-21, Last modification date: 2023-09-13)
Primary citationLaganowsky, A.,Liu, C.,Sawaya, M.R.,Whitelegge, J.P.,Park, J.,Zhao, M.,Pensalfini, A.,Soriaga, A.B.,Landau, M.,Teng, P.K.,Cascio, D.,Glabe, C.,Eisenberg, D.
Atomic view of a toxic amyloid small oligomer.
Science, 335:1228-1231, 2012
Cited by
PubMed: 22403391
DOI: 10.1126/science.1213151
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4016 Å)
Structure validation

217705

건을2024-03-27부터공개중

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