3SFM

Novel crystallization conditions for tandem variant R67 DHFR yields wild-type crystal structure

3SFM の概要

• エントリーDOI: 10.2210/pdb3sfm/pdb
• 分子名称: Dihydrofolate reductase type 2, (4R)-2-METHYLPENTANE-2,4-DIOL (3 entities in total)
• 機能のキーワード: oxidoreductase, dihydrofolate reductase, antibiotic resistance, in situ proteolysis, type ii dhfr, sh3, reductase, dhf and nadph-binding
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 7088.03

構造登録者

Yachnin, B.J.,Berghuis, A.M. (登録日: 2011-06-13, 公開日: 2011-11-02, 最終更新日: 2023-09-13)

• 主引用文献: Yachnin, B.J.,Colin, D.Y.,Volpato, J.P.,Ebert, M.,Pelletier, J.N.,Berghuis, A.M.; Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure.; Acta Crystallogr.,Sect.F, 67:1316-1322, 2011; PubMed: 22102224; DOI: 10.1107/S1744309111030417

実験手法

X-RAY DIFFRACTION (1.4 Å)