3SF4

Crystal structure of the complex between the conserved cell polarity proteins Inscuteable and LGN

Summary for 3SF4

• Entry DOI: 10.2210/pdb3sf4/pdb
• Descriptor: G-protein-signaling modulator 2, Protein inscuteable homolog (3 entities in total)
• Functional Keywords: tetratricopeptide repeat, tpr, cell polarity, asymmetric cell division, mitotic spindle orientation, cytoplasm and cell cortex, signaling protein-protein binding complex, signaling protein/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P81274 Q1MX18
• Total number of polymer chains: 6
• Total formula weight: 151637.23

Authors

Yuzawa, S.,Kamakura, S.,Iwakiri, Y.,Hayase, J.,Sumimoto, H. (deposition date: 2011-06-12, release date: 2011-11-23, Last modification date: 2023-11-01)

• Primary citation: Yuzawa, S.,Kamakura, S.,Iwakiri, Y.,Hayase, J.,Sumimoto, H.; Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN); Proc.Natl.Acad.Sci.USA, 108:19210-19215, 2011; PubMed: 22074847; DOI: 10.1073/pnas.1110951108

Experimental method

X-RAY DIFFRACTION (2.6 Å)