3SF4

Crystal structure of the complex between the conserved cell polarity proteins Inscuteable and LGN

Summary for 3SF4

DescriptorG-protein-signaling modulator 2, Protein inscuteable homolog (3 entities in total)
Functional Keywordstetratricopeptide repeat, tpr, cell polarity, asymmetric cell division, mitotic spindle orientation, cytoplasm and cell cortex, signaling protein-protein binding complex, signaling protein/protein binding
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P81274 Q1MX18
Total number of polymer chains6
Total molecular weight151637.23
Authors
Yuzawa, S.,Kamakura, S.,Iwakiri, Y.,Hayase, J.,Sumimoto, H. (deposition date: 2011-06-12, release date: 2011-11-23, Last modification date: 2013-06-19)
Primary citation
Yuzawa, S.,Kamakura, S.,Iwakiri, Y.,Hayase, J.,Sumimoto, H.
Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)
Proc.Natl.Acad.Sci.USA, 108:19210-19215, 2011
PubMed: 22074847 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1110951108
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.220110.1%1.4%5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution