3SAA
Crystal structure of Wild-type HIV-1 protease in complex With AF77
Summary for 3SAA
Entry DOI | 10.2210/pdb3saa/pdb |
Related | 3SA3 3SA4 3SA5 3SA6 3SA7 3SA8 3SA9 3SAB 3SAC |
Related PRD ID | PRD_000953 |
Descriptor | Protease, PHOSPHATE ION, N-[(2S,3R)-4-{(cyclohexylmethyl)[(4-methoxyphenyl)sulfonyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-3-hydroxybenzamide, ... (4 entities in total) |
Functional Keywords | hiv-1 protease, drug resistance, drug design, protease inhibitors, aids, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 22388.23 |
Authors | Schiffer, C.A.,Nalam, M.N.L. (deposition date: 2011-06-02, release date: 2012-06-06, Last modification date: 2023-09-13) |
Primary citation | Altman, M.D.,Nalam, M.N.L.,Ali, A.,Cao, H.,Rana, T.M.,Schiffer, C.A.,Tidor, B. Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published, |
Experimental method |
Structure validation
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