3S48

Human Alpha-Haemoglobin Complexed with the First NEAT Domain of IsdH from Staphylococcus aureus

Summary for 3S48

• Entry DOI: 10.2210/pdb3s48/pdb
• Related: 3OVU
• Descriptor: Iron-regulated surface determinant protein H, Hemoglobin subunit alpha, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
• Functional Keywords: haemoglobin, neat domain, isdh, protein-protein complex, host-pathogen interaction, oxygen transport-protein binding complex, oxygen transport/protein binding
• Biological source: Staphylococcus aureus; More
• Cellular location: Secreted, cell wall; Peptidoglycan-anchor (Potential): Q6G8J7
• Total number of polymer chains: 4
• Total formula weight: 69343.33

Authors

Kumar, K.K.,Jacques, D.A.,Caradoc-Davies, T.T.,Guss, J.M.,Gell, D.A. (deposition date: 2011-05-19, release date: 2012-05-23, Last modification date: 2023-11-01)

• Primary citation: Krishna Kumar, K.,Jacques, D.A.,Guss, J.M.,Gell, D.A.; The structure of alpha-haemoglobin in complex with a haemoglobin-binding domain from Staphylococcus aureus reveals the elusive alpha-haemoglobin dimerization interface; ACTA CRYSTALLOGR.,SECT.F, 70:1032-1037, 2014; PubMed: 25084376; DOI: 10.1107/S2053230X14012175

Experimental method

X-RAY DIFFRACTION (3.05 Å)