3S24

Crystal structure of human mRNA guanylyltransferase

Summary for 3S24

Entry DOI	10.2210/pdb3s24/pdb
Related	1CKM 1CKN 1CKO 1P16 2C46
Descriptor	mRNA-capping enzyme, SULFATE ION (2 entities in total)
Functional Keywords	capping enzyme, ce, hce, gtase, m7gpppn cap, gt/dna ligase fold, transcription factor spt5, ctd, hydrolase, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus (By similarity): O60942
Total number of polymer chains	7
Total formula weight	280403.20
Authors	Das, K.,Chu, C.,Thyminski, J.R.,Bauman, J.D.,Guan, R.,Qiu, W.,Montelione, G.T.,Arnold, E.,Shatkin, A.J. (deposition date: 2011-05-16, release date: 2011-06-15, Last modification date: 2023-09-13)
Primary citation	Chu, C.,Das, K.,Tyminski, J.R.,Bauman, J.D.,Guan, R.,Qiu, W.,Montelione, G.T.,Arnold, E.,Shatkin, A.J. Structure of the guanylyltransferase domain of human mRNA capping enzyme. Proc.Natl.Acad.Sci.USA, 108:10104-10108, 2011 Cited by PubMed: 21636784 DOI: 10.1073/pnas.1106610108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.0137 Å)

Structure validation