3S24

Crystal structure of human mRNA guanylyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	mRNA-capping enzyme	polymer	347	39989.0	7	UniProt (O60942) Pfam (PF01331) Pfam (PF03919) In PDB	Homo sapiens (human)	HCAP1, HCE, Polynucleotide 5'-triphosphatase, mRNA 5'capping, TPase, mRNA guanylyltransferase, GTase
2	A, B	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)

Sequence modifications

A, B, C, D, E, G, F: 229 - 567 (UniProt: O60942)

PDB	External Database	Details
Leu 568	-	expression tag
Glu 569	-	expression tag
His 570	-	expression tag
His 571	-	expression tag
His 572	-	expression tag
His 573	-	expression tag
His 574	-	expression tag
His 575	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	279922.9
Non-Polymers*	Number of molecules	5
	Total formula weight	480.3
All*	Total formula weight	280403.2

*Water molecules are not included.