3RZI

The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan

3RZI の概要

• エントリーDOI: 10.2210/pdb3rzi/pdb
• 関連するPDBエントリー: 3KGF 3NUD 3NUE 3NV8
• 分子名称: Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, PHENYLALANINE, ... (9 entities in total)
• 機能のキーワード: dah7p synthase, shikimate pathway, aromatic biosynthesis, evolutionary relationships, transferase, phe+trp-bound, augmented tim-barrel structure, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, tim barrel
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 103631.09

構造登録者

Jiao, W.,Jameson, G.B.,Hutton, R.D.,Parker, E.J. (登録日: 2011-05-11, 公開日: 2012-01-25, 最終更新日: 2023-11-01)

• 主引用文献: Jiao, W.,Hutton, R.D.,Cross, P.J.,Jameson, G.B.,Parker, E.J.; Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery.; J.Mol.Biol., 415:716-726, 2012; PubMed: 22154807; DOI: 10.1016/j.jmb.2011.11.037

実験手法

X-RAY DIFFRACTION (1.95 Å)