3RY6

Complex of fcgammariia (CD32) and the FC of human IGG1

3RY6 の概要

• エントリーDOI: 10.2210/pdb3ry6/pdb
• 関連するPDBエントリー: 3RY4 3RY5
• 分子名称: Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-a, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: fc receptor, cd32, immunoglobulin superfamily, high responder polymorphism, human igg1, therapeutic antibody, glycoprotein, immunoglobulin c region, immunoglobulin domain, cell membrane, igg-binding protein, membrane, phosphoprotein, receptor, transmembrane, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 73303.44

構造登録者

Ramsland, P.A.,Farrugia, W.,Scott, A.M.,Hogarth, P.M. (登録日: 2011-05-11, 公開日: 2011-08-31, 最終更新日: 2023-09-13)

• 主引用文献: Ramsland, P.A.,Farrugia, W.,Bradford, T.M.,Sardjono, C.T.,Esparon, S.,Trist, H.M.,Powell, M.S.,Tan, P.S.,Cendron, A.C.,Wines, B.D.,Scott, A.M.,Hogarth, P.M.; Structural Basis for Fc{gamma}RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes.; J.Immunol., 187:3208-3217, 2011; PubMed: 21856937; DOI: 10.4049/jimmunol.1101467

実験手法

X-RAY DIFFRACTION (3.8 Å)