3ROP
Crystal structure of human CD38 in complex with compound CZ-50b
Summary for 3ROP
Entry DOI | 10.2210/pdb3rop/pdb |
Related | 1YH3 3ROK 3ROM 3ROQ |
Descriptor | ADP-ribosyl cyclase 1, 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-ribofuranose, NICOTINAMIDE, ... (4 entities in total) |
Functional Keywords | cd38, adp-ribosyl cyclase, cyclic adp-ribose, x-crystallography, calcium signaling, inhibitory compound, covalent intermediate, cz-50b, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 59787.41 |
Authors | |
Primary citation | Kwong, A.K.,Chen, Z.,Zhang, H.,Leung, F.P.,Lam, C.M.,Ting, K.Y.,Zhang, L.,Hao, Q.,Zhang, L.H.,Lee, H.C. Catalysis-based inhibitors of the calcium signaling function of CD38. Biochemistry, 51:555-564, 2012 Cited by PubMed: 22142305DOI: 10.1021/bi201509f PDB entries with the same primary citation |
Experimental method |
Structure validation
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