3RN6

Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with zinc and isoguanine

Summary for 3RN6

• Entry DOI: 10.2210/pdb3rn6/pdb
• Related: 3O7U
• Descriptor: Cytosine deaminase, (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, ZINC ION, ... (5 entities in total)
• Functional Keywords: amidohydrolase fold, cytosine deaminase, isoguanine, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 48295.19

Authors

Fedorov, A.A.,Fedorov, E.V.,Hitchcock, D.S.,Raushel, F.M.,Almo, S.C. (deposition date: 2011-04-22, release date: 2011-08-24, Last modification date: 2023-09-13)

• Primary citation: Hitchcock, D.S.,Fedorov, A.A.,Fedorov, E.V.,Dangott, L.J.,Almo, S.C.,Raushel, F.M.; Rescue of the orphan enzyme isoguanine deaminase.; Biochemistry, 50:5555-5557, 2011; PubMed: 21604715; DOI: 10.1021/bi200680y

Experimental method

X-RAY DIFFRACTION (2.255 Å)