3RLH

Crystal structure of a class II phospholipase D from Loxosceles intermedia venom

Summary for 3RLH

• Entry DOI: 10.2210/pdb3rlh/pdb
• Related: 3RLG
• Descriptor: Sphingomyelin phosphodiesterase D LiSicTox-alphaIA1a, MAGNESIUM ION, TRIETHYLENE GLYCOL, ... (6 entities in total)
• Functional Keywords: class ii pld, tim beta/alpha-barrel superfamily, plc-like phosphodiesterase, phospholipase d, venom, hydrolase
• Biological source: Loxosceles intermedia (Spider)
• Cellular location: Secreted: P0CE80
• Total number of polymer chains: 1
• Total formula weight: 37454.20

Authors

Giuseppe, P.O.,Ullah, A.,Veiga, S.S.,Murakami, M.T.,Arni, R.K. (deposition date: 2011-04-19, release date: 2011-06-29, Last modification date: 2023-09-13)

• Primary citation: de Giuseppe, P.O.,Ullah, A.,Silva, D.T.,Gremski, L.H.,Wille, A.C.,Chaves Moreira, D.,Ribeiro, A.S.,Chaim, O.M.,Murakami, M.T.,Veiga, S.S.,Arni, R.K.; Structure of a novel class II phospholipase D: Catalytic cleft is modified by a disulphide bridge.; Biochem.Biophys.Res.Commun., 409:622-627, 2011; PubMed: 21616057; DOI: 10.1016/j.bbrc.2011.05.053

Experimental method

X-RAY DIFFRACTION (1.72 Å)