3RF5

Ancylostoma ceylanicum mif in complex with n-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide

Summary for 3RF5

• Entry DOI: 10.2210/pdb3rf5/pdb
• Related: 2OS5 3RF4
• Descriptor: Macrophage migration inhibitory factor, 2-[(furan-2-ylmethyl)amino]benzoic acid, IMIDAZOLE, ... (6 entities in total)
• Functional Keywords: protein-small molecule complex, isomerase, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: Ancylostoma ceylanicum
• Total number of polymer chains: 3
• Total formula weight: 39885.92

Authors

Cho, Y.,Lolis, E. (deposition date: 2011-04-05, release date: 2011-10-12, Last modification date: 2023-09-13)

• Primary citation: Cho, Y.,Vermeire, J.J.,Merkel, J.S.,Leng, L.,Du, X.,Bucala, R.,Cappello, M.,Lolis, E.; Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.; Chem.Biol., 18:1089-1101, 2011; PubMed: 21944748; DOI: 10.1016/j.chembiol.2011.07.011

Experimental method

X-RAY DIFFRACTION (2.1 Å)