3REV
Crystal structure of human alloreactive tcr nb20
Summary for 3REV
Entry DOI | 10.2210/pdb3rev/pdb |
Related | 3REW |
Descriptor | TCR NB20 ALPHA CHAIN, TCR NB20 BETA CHAIN, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | t cell receptor, mhc class i, tumour antigen, immune system, immune response, alloreactivity, immunoglobulin domain |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 49665.27 |
Authors | Wood, A.,Mohammed, F.,Salim, M.,Tranter, A.,Rickinson, A.B.,Moss, P.A.H.,Stauss, H.J.,Steven, N.M.,Willcox, B.E. (deposition date: 2011-04-05, release date: 2012-01-18) |
Primary citation | Simpson, A.A.,Mohammed, F.,Salim, M.,Tranter, A.,Rickinson, A.B.,Stauss, H.J.,Moss, P.A.,Steven, N.M.,Willcox, B.E. Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction. Proc.Natl.Acad.Sci.USA, 108:21176-21181, 2011 Cited by PubMed: 22160697DOI: 10.1073/pnas.1108422109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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