3REV

Crystal structure of human alloreactive tcr nb20

Summary for 3REV

Related3REW
DescriptorTCR NB20 ALPHA CHAIN, TCR NB20 BETA CHAIN, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordst cell receptor, mhc class i, tumour antigen, immune system, immune response, alloreactivity, immunoglobulin domain
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight49665.27
Authors
Primary citation
Simpson, A.A.,Mohammed, F.,Salim, M.,Tranter, A.,Rickinson, A.B.,Stauss, H.J.,Moss, P.A.,Steven, N.M.,Willcox, B.E.
Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction.
Proc.Natl.Acad.Sci.USA, 108:21176-21181, 2011
PubMed: 22160697 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1108422109
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.266140.7%3.9%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3rev
no rotation
Molmil generated image of 3rev
rotated about x axis by 90°
Molmil generated image of 3rev
rotated about y axis by 90°