3REV

Crystal structure of human alloreactive tcr nb20

Summary for 3REV

• Entry DOI: 10.2210/pdb3rev/pdb
• Related: 3REW
• Descriptor: TCR NB20 ALPHA CHAIN, TCR NB20 BETA CHAIN, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: t cell receptor, mhc class i, tumour antigen, immune system, immune response, alloreactivity, immunoglobulin domain
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 49665.27

Authors

Wood, A.,Mohammed, F.,Salim, M.,Tranter, A.,Rickinson, A.B.,Moss, P.A.H.,Stauss, H.J.,Steven, N.M.,Willcox, B.E. (deposition date: 2011-04-05, release date: 2012-01-18)

• Primary citation: Simpson, A.A.,Mohammed, F.,Salim, M.,Tranter, A.,Rickinson, A.B.,Stauss, H.J.,Moss, P.A.,Steven, N.M.,Willcox, B.E.; Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction.; Proc.Natl.Acad.Sci.USA, 108:21176-21181, 2011; PubMed: 22160697; DOI: 10.1073/pnas.1108422109

Experimental method

X-RAY DIFFRACTION (2.2 Å)