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3RDE

Crystal structure of the catalytic domain of porcine leukocyte 12-lipoxygenase

Summary for 3RDE
Entry DOI10.2210/pdb3rde/pdb
DescriptorArachidonate 12-lipoxygenase, 12S-type, POTASSIUM ION, FE (II) ION, ... (5 entities in total)
Functional Keywordslipoxygenase, c-terminal domain, protein-inhibitor complex, 4-(2-oxapentadeca-4-yne)phenylpropanoic acid, lipoxygenase catalytic domain, dioxygenase, fe, leukocyte, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceSus scrofa (pigs,swine,wild boar)
Cellular locationCytoplasm: P16469
Total number of polymer chains4
Total formula weight260800.54
Authors
Funk, M.O.,Xu, S.,Marnett, L.J.,Mueser, T.C. (deposition date: 2011-04-01, release date: 2012-04-18, Last modification date: 2023-09-13)
Primary citationXu, S.,Mueser, T.C.,Marnett, L.J.,Funk, M.O.
Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis.
Structure, 20:1490-1497, 2012
Cited by
PubMed: 22795085
DOI: 10.1016/j.str.2012.06.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.892 Å)
Structure validation

217705

数据于2024-03-27公开中

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