3QRF

Structure of a domain-swapped FOXP3 dimer

3QRF の概要

関連するPDBエントリー1a02 1owr 2as5 2a07
分子名称Nuclear factor of activated T-cells, cytoplasmic 2, Forkhead box protein P3, human hARRE2 DNA (Plus Strand), ... (6 entities in total)
機能のキーワードbeta barrel, domain swap, forkhead domain, immnoglobulin fold, protein-dna complex, double helix, transcription regulation, dna binding, nucleus, dna binding protein-dna complex, dna binding protein/dna
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Cytoplasm Q13469
Nucleus  Q9BZS1
ポリマー鎖数10
分子量合計130608.36
構造登録者
Bandukwala, H.S.,Wu, Y.,Feurer, M.,Chen, Y.,Barbosa, B.,Ghosh, S.,Stroud, J.C.,Benoist, C.,Mathis, D.,Rao, A.,Chen, L. (登録日: 2011-02-17, 公開日: 2011-04-20, 最終更新日: 2018-01-24)
主引用文献
Bandukwala, H.S.,Wu, Y.,Feuerer, M.,Chen, Y.,Barboza, B.,Ghosh, S.,Stroud, J.C.,Benoist, C.,Mathis, D.,Rao, A.,Chen, L.
Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Immunity, 34:479-491, 2011
PubMed: 21458306 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.immuni.2011.02.017
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.8 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.278326.8%6.8%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード