3QOW

DOT1L Structure in complex with SAM

Summary for 3QOW

• Entry DOI: 10.2210/pdb3qow/pdb
• Related: 3QOX
• Descriptor: Histone-lysine N-methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: h3k79 methylation, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Probable): Q8TEK3
• Total number of polymer chains: 1
• Total formula weight: 49287.99

Authors

Jin, L. (deposition date: 2011-02-11, release date: 2011-05-25, Last modification date: 2024-02-21)

• Primary citation: Richon, V.M.,Johnston, D.,Sneeringer, C.J.,Jin, L.,Majer, C.R.,Elliston, K.,Jerva, L.F.,Scott, M.P.,Copeland, R.A.; Chemogenetic analysis of human protein methyltransferases.; Chem.Biol.Drug Des., 78:199-210, 2011; PubMed: 21564555; DOI: 10.1111/j.1747-0285.2011.01135.x

Experimental method

X-RAY DIFFRACTION (2.1 Å)