3QLP

X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA)

Summary for 3QLP

• Entry DOI: 10.2210/pdb3qlp/pdb
• Related PRD ID: PRD_000020
• Descriptor: Thrombin heavy chain, Thrombin light chain, modified thrombin binding DNA aptamer, ... (8 entities in total)
• Functional Keywords: protein-dna complex, serine protease, blood coagulation, aptamer, serine protease fold, hydrolase-hydrolase inhibitor-dna complex, hydrolase/hydrolase inhibitor/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 39357.09

Authors

Russo Krauss, I.,Merlino, A.,Mazzarella, L.,Sica, F. (deposition date: 2011-02-03, release date: 2011-10-19, Last modification date: 2020-07-29)

• Primary citation: Russo Krauss, I.,Merlino, A.,Giancola, C.,Randazzo, A.,Mazzarella, L.,Sica, F.; Thrombin-aptamer recognition: a revealed ambiguity.; Nucleic Acids Res., 39:7858-7867, 2011; PubMed: 21715374; DOI: 10.1093/nar/gkr522

Experimental method

X-RAY DIFFRACTION (2.14 Å)