3QIH

HIV-1 protease (mutant Q7K L33I L63I) in complex with a novel inhibitor

Summary for 3QIH

• Entry DOI: 10.2210/pdb3qih/pdb
• Descriptor: Protease, ethyl 3-aminobenzoate, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus type 1 (BRU ISOLATE) (HIV-1)
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367
• Total number of polymer chains: 2
• Total formula weight: 22563.92

Authors

Lindemann, I.,Heine, A.,Klebe, G. (deposition date: 2011-01-27, release date: 2012-02-01, Last modification date: 2023-11-01)

• Primary citation: Lindemann, I.,Klee, N.,Heine, A.,Diederich, W.E.,Klebe, G.; Novel inhibitors for HIV-1 protease; To be Published,

Experimental method

X-RAY DIFFRACTION (1.39 Å)