3QFJ
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified TAX (Y5F) peptide
Summary for 3QFJ
Entry DOI | 10.2210/pdb3qfj/pdb |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, TAX(Y5F) peptide, ... (7 entities in total) |
Functional Keywords | tax peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, y5f mutation, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 5 |
Total formula weight | 95250.40 |
Authors | Borbulevych, O.Y.,Baker, B.M. (deposition date: 2011-01-21, release date: 2012-01-11, Last modification date: 2023-09-13) |
Primary citation | Scott, D.R.,Borbulevych, O.Y.,Piepenbrink, K.H.,Corcelli, S.A.,Baker, B.M. Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism. J.Mol.Biol., 414:385-400, 2011 Cited by PubMed: 22019736DOI: 10.1016/j.jmb.2011.10.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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