3QDZ
Crystal structure of the human thrombin mutant D102N in complex with the extracellular fragment of human PAR4.
Summary for 3QDZ
Entry DOI | 10.2210/pdb3qdz/pdb |
Related | 1SHH |
Descriptor | Thrombin light chain, Thrombin heavy chain, Proteinase-activated receptor 4 (3 entities in total) |
Functional Keywords | serine protease, protein function, protease-activated receptors, hydrolase-hydrolase receptor complex, hydrolase/hydrolase receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Cell membrane; Multi-pass membrane protein: Q96RI0 |
Total number of polymer chains | 6 |
Total formula weight | 68756.87 |
Authors | Gandhi, P.,Chen, Z.,Appelbaum, E.,Zapata, F.,Di Cera, E. (deposition date: 2011-01-19, release date: 2011-06-29, Last modification date: 2023-09-13) |
Primary citation | Gandhi, P.S.,Chen, Z.,Appelbaum, E.,Zapata, F.,Di Cera, E. Structural basis of thrombin-protease-receptor interactions IUBMB LIFE, 63:375-382, 2011 |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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