3QBV
Structure of designed orthogonal interaction between CDC42 and nucleotide exchange domains of intersectin
3QBV の概要
エントリーDOI | 10.2210/pdb3qbv/pdb |
関連するPDBエントリー | 1KI1 |
分子名称 | Cell division control protein 42 homolog, Intersectin-1, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total) |
機能のキーワード | computationally designed, orthogonal interaction, gtpase, nucleotide exchange, cell membrane, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, cell junction, cell projection, endocytosis, phosphoprotein, sh3 domain, synapse, synaptosome, protein binding-signaling protein complex, protein binding/signaling protein |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953 Endomembrane system (By similarity): Q15811 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 121928.46 |
構造登録者 | |
主引用文献 | Kapp, G.T.,Liu, S.,Stein, A.,Wong, D.T.,Remenyi, A.,Yeh, B.J.,Fraser, J.S.,Taunton, J.,Lim, W.A.,Kortemme, T. Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair. Proc.Natl.Acad.Sci.USA, 109:5277-5282, 2012 Cited by PubMed: 22403064DOI: 10.1073/pnas.1114487109 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.65 Å) |
構造検証レポート
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