3QB7

Interleukin-4 mutant RGA bound to cytokine receptor common gamma

3QB7 の概要

• エントリーDOI: 10.2210/pdb3qb7/pdb
• 分子名称: Interleukin 4, Cytokine receptor common subunit gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: cytokine signaling, il-4ralpha, cytokine-cytokine receptor complex, cytokine/cytokine receptor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 80630.74

構造登録者

Bates, D.L.,Junttila, I.S.,Creusot, R.J.,Moraga, I.,Lupardus, P.,Fathman, C.G.,Paul, W.E.,Garcia, K.C. (登録日: 2011-01-12, 公開日: 2012-04-25, 最終更新日: 2023-12-27)

• 主引用文献: Junttila, I.S.,Creusot, R.J.,Moraga, I.,Bates, D.L.,Wong, M.T.,Alonso, M.N.,Suhoski, M.M.,Lupardus, P.,Meier-Schellersheim, M.,Engleman, E.G.,Utz, P.J.,Fathman, C.G.,Paul, W.E.,Garcia, K.C.; Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines.; Nat.Chem.Biol., 8:990-998, 2012; PubMed: 23103943; DOI: 10.1038/nchembio.1096

実験手法

X-RAY DIFFRACTION (3.245 Å)