3Q81

Imipenem acylated BlaR1 sensor domain from Staphylococcus aureus

3Q81 の概要

• エントリーDOI: 10.2210/pdb3q81/pdb
• 関連するPDBエントリー: 1XA1 3Q7V 3Q7Z 3Q82
• 分子名称: Beta-lactamase regulatory protein BlaR1, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: antibiotic-binding, mrsa, antibiotic-binding-antibiotic complex, hydrolase regulator-antibiotic complex, hydrolase regulator/antibiotic
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59865.32

構造登録者

Borbulevych, O.Y.,Mobashery, S.,Baker, B.M. (登録日: 2011-01-05, 公開日: 2011-07-20, 最終更新日: 2013-01-09)

• 主引用文献: Borbulevych, O.,Kumarasiri, M.,Wilson, B.,Llarrull, L.I.,Lee, M.,Hesek, D.,Shi, Q.,Peng, J.,Baker, B.M.,Mobashery, S.; Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.; J.Biol.Chem., 286:31466-31472, 2011; PubMed: 21775440; DOI: 10.1074/jbc.M111.252189

実験手法

X-RAY DIFFRACTION (2 Å)