3Q6U

Structure of the apo MET receptor kinase in the dually-phosphorylated, activated state

Summary for 3Q6U

Entry DOI	10.2210/pdb3q6u/pdb
Related	3Q6W
Descriptor	Hepatocyte growth factor receptor (2 entities in total)
Functional Keywords	tyrosine kinase, transferase
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: P08581
Total number of polymer chains	1
Total formula weight	35126.64
Authors	Soisson, S.M.,Rickert, K.W.,Patel, S.B.,Allison, T.,Lumb, K.J. (deposition date: 2011-01-03, release date: 2011-01-19, Last modification date: 2011-07-13)
Primary citation	Rickert, K.W.,Patel, S.B.,Allison, T.J.,Byrne, N.J.,Darke, P.L.,Ford, R.E.,Guerin, D.J.,Hall, D.L.,Kornienko, M.,Lu, J.,Munshi, S.K.,Reid, J.C.,Shipman, J.M.,Stanton, E.F.,Wilson, K.J.,Young, J.R.,Soisson, S.M.,Lumb, K.J. Structural basis for selective small molecule kinase inhibition of activated c-Met. J.Biol.Chem., 286:11218-11225, 2011 Cited by PubMed: 21247903 DOI: 10.1074/jbc.M110.204404 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation