3Q23
X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II
Summary for 3Q23
Entry DOI | 10.2210/pdb3q23/pdb |
Related | 3Q0A 3Q22 3Q24 |
Descriptor | Virion RNA polymerase, DNA (5'-D(*TP*GP*CP*CP*TP*CP*CP*CP*AP*GP*GP*CP*AP*TP*CP*CP*AP*AP*AP*AP*GP*AP*AP*GP*CP*GP*GP*AP*GP*CP*TP*TP*CP*TP*TP*C)-3'), PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (6 entities in total) |
Functional Keywords | protein-dna complex, two-metal catalysis, gmpcpp, gpcpp, de novo transcription initiation, nucleotidyltransferase, initiation complex, dna-hairpin, virion rna polymerase, phosphate ion, rna polymerase, transferase-dna complex, transferase/dna |
Biological source | Enterobacteria phage N4 (Bacteriophage N4) |
Total number of polymer chains | 4 |
Total formula weight | 270899.74 |
Authors | Gleghorn, M.L.,Murakami, K.S. (deposition date: 2010-12-19, release date: 2011-02-16, Last modification date: 2024-02-21) |
Primary citation | Gleghorn, M.L.,Davydova, E.K.,Basu, R.,Rothman-Denes, L.B.,Murakami, K.S. X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides. Proc.Natl.Acad.Sci.USA, 108:3566-3571, 2011 Cited by PubMed: 21321236DOI: 10.1073/pnas.1016691108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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