3Q23
X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE G2P A 1108 |
| Chain | Residue |
| A | ARG424 |
| A | ARG666 |
| A | LYS670 |
| A | ASN671 |
| A | TYR678 |
| A | ASP951 |
| A | MN1107 |
| A | MN1109 |
| A | G2P1111 |
| A | HOH1128 |
| A | HOH1221 |
| A | ASP559 |
| A | HOH1239 |
| A | HOH1455 |
| A | HOH1569 |
| A | HOH1615 |
| A | HOH1644 |
| A | HOH1866 |
| C | DC4 |
| C | DC5 |
| A | GLY560 |
| A | VAL561 |
| A | THR562 |
| A | ASN563 |
| A | GLY564 |
| A | PRO565 |
| A | TYR612 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 1107 |
| Chain | Residue |
| A | ASP559 |
| A | ASP951 |
| A | G2P1108 |
| A | MN1109 |
| A | G2P1111 |
| A | HOH2284 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 1109 |
| Chain | Residue |
| A | ASP559 |
| A | GLY560 |
| A | ASP951 |
| A | MN1107 |
| A | G2P1108 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2HP A 1110 |
| Chain | Residue |
| A | GLN469 |
| A | ILE473 |
| A | LYS474 |
| A | VAL475 |
| A | HIS476 |
| A | HOH1220 |
| A | HOH1415 |
| A | HOH1603 |
| A | HOH2042 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE G2P A 1111 |
| Chain | Residue |
| A | ARG424 |
| A | LYS437 |
| A | GLU557 |
| A | ASP559 |
| A | ILE925 |
| A | PHE950 |
| A | ASP951 |
| A | MN1107 |
| A | G2P1108 |
| A | HOH1221 |
| A | HOH1615 |
| A | HOH2102 |
| A | HOH2272 |
| A | HOH2284 |
| A | HOH2285 |
| A | HOH2286 |
| A | HOH2287 |
| A | HOH2288 |
| A | HOH2289 |
| A | HOH2291 |
| A | HOH2295 |
| A | HOH2296 |
| A | HOH2297 |
| A | HOH2298 |
| C | DC5 |
| C | DA6 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE G2P B 1108 |
| Chain | Residue |
| B | ARG424 |
| B | LYS437 |
| B | GLU557 |
| B | ASP559 |
| B | ILE925 |
| B | PHE950 |
| B | ASP951 |
| B | MN1107 |
| B | G2P1109 |
| B | HOH1719 |
| B | HOH1767 |
| B | HOH1863 |
| B | HOH1968 |
| B | HOH2106 |
| B | HOH2239 |
| B | HOH2341 |
| B | HOH2460 |
| B | HOH2608 |
| B | HOH2720 |
| B | HOH2767 |
| B | HOH2780 |
| B | HOH2849 |
| D | DC5 |
| D | DA6 |
| site_id | AC7 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE G2P B 1109 |
| Chain | Residue |
| B | GLY560 |
| B | VAL561 |
| B | THR562 |
| B | ASN563 |
| B | GLY564 |
| B | PRO565 |
| B | TYR612 |
| B | ARG666 |
| B | LYS670 |
| B | ASN671 |
| B | TYR678 |
| B | ASP951 |
| B | MN1107 |
| B | G2P1108 |
| B | MN1110 |
| B | HOH1775 |
| B | HOH1803 |
| B | HOH1968 |
| B | HOH1994 |
| B | HOH2106 |
| B | HOH2114 |
| B | HOH2332 |
| B | HOH2411 |
| B | HOH2767 |
| D | DC4 |
| D | DC5 |
| B | ARG424 |
| B | ASP559 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 1107 |
| Chain | Residue |
| B | ASP559 |
| B | ASP951 |
| B | G2P1108 |
| B | G2P1109 |
| B | MN1110 |
| B | HOH1767 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 1110 |
| Chain | Residue |
| B | ASP559 |
| B | GLY560 |
| B | ASP951 |
| B | MN1107 |
| B | G2P1109 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2HP B 1111 |
| Chain | Residue |
| B | GLN469 |
| B | ILE473 |
| B | LYS474 |
| B | VAL475 |
| B | HIS476 |
| B | HOH1857 |
| B | HOH2400 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21321236","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23235152","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
