3PXK
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH Pyrrolo[2,3-d]thiazole
Summary for 3PXK
Entry DOI | 10.2210/pdb3pxk/pdb |
Descriptor | PTK2 protein, 6-(4,4-dimethylpent-2-ynyl)-4~{H}-pyrrolo[2,3-d][1,3]thiazole, SULFATE ION, ... (4 entities in total) |
Functional Keywords | tyrosine protein kinase, transferase, atp binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 65141.14 |
Authors | Koolman, H.,Heinrich, T.,Musil, D. (deposition date: 2010-12-10, release date: 2011-12-21, Last modification date: 2023-09-13) |
Primary citation | Koolman, H.,Heinrich, T.,Musil, D. Co-crystal Structures of FAK with an Unprecedented Pyrrolo[2,3-d]thiazole To be Published, |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
Download full validation report