3PWH
Thermostabilised Adenosine A2A Receptor
Summary for 3PWH
Entry DOI | 10.2210/pdb3pwh/pdb |
Descriptor | Adenosine receptor A2a, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol (2 entities in total) |
Functional Keywords | 7tm, gpcr, inverse agonist, g-protein, membrane protein, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Multi-pass membrane protein: P29274 |
Total number of polymer chains | 1 |
Total formula weight | 36816.44 |
Authors | Dore, A.S.,Robertson, N.,Errey, J.C.,Ng, I.,Tehan, B.,Hurrell, E.,Magnani, F.,Tate, C.G.,Weir, M.,Marshall, F.H. (deposition date: 2010-12-08, release date: 2011-09-07, Last modification date: 2023-11-01) |
Primary citation | Dore, A.S.,Robertson, N.,Errey, J.C.,Ng, I.,Hollenstein, K.,Tehan, B.,Hurrell, E.,Bennett, K.,Congreve, M.,Magnani, F.,Tate, C.G.,Weir, M.,Marshall, F.H. Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine Structure, 19:1283-1293, 2011 Cited by PubMed: 21885291DOI: 10.1016/j.str.2011.06.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.296 Å) |
Structure validation
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