3PUF
Crystal structure of human RNase H2 complex
Summary for 3PUF
Entry DOI | 10.2210/pdb3puf/pdb |
Descriptor | Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C, ... (4 entities in total) |
Functional Keywords | rnase h fold, triple barrel fold, hydrolase, rnase h |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): O75792 Q5TBB1 Q8TDP1 |
Total number of polymer chains | 18 |
Total formula weight | 465896.12 |
Authors | Figiel, M.,Chon, H.,Cerritelli, S.M.,Cybulska, M.,Crouch, R.J.,Nowotny, M. (deposition date: 2010-12-04, release date: 2010-12-22, Last modification date: 2023-11-01) |
Primary citation | Figiel, M.,Chon, H.,Cerritelli, S.M.,Cybulska, M.,Crouch, R.J.,Nowotny, M. The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutieres syndrome defects. J.Biol.Chem., 286:10540-10550, 2011 Cited by PubMed: 21177858DOI: 10.1074/jbc.M110.181974 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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