3PMA

2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate

Summary for 3PMA

• Entry DOI: 10.2210/pdb3pma/pdb
• Related: 3PMB
• Related PRD ID: PRD_900013
• Descriptor: Thrombin light chain, Thrombin heavy chain, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: protease, thrombosis, fibrinolysis, agonist, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bos taurus (bovine,cow,domestic cattle,domestic cow); More
• Total number of polymer chains: 4
• Total formula weight: 68896.37

Authors

Wright, H.T.,Scarsdale, J.N.,Desai, B.J. (deposition date: 2010-11-16, release date: 2011-07-20, Last modification date: 2023-09-06)

• Primary citation: Desai, B.J.,Boothello, R.S.,Mehta, A.Y.,Scarsdale, J.N.,Wright, H.T.,Desai, U.R.; Interaction of thrombin with sucrose octasulfate.; Biochemistry, 50:6973-6982, 2011; PubMed: 21736375; DOI: 10.1021/bi2004526

Experimental method

X-RAY DIFFRACTION (2.2 Å)