3PKI
Human SIRT6 crystal structure in complex with ADP ribose
Summary for 3PKI
Entry DOI | 10.2210/pdb3pki/pdb |
Related | 3PKJ |
Descriptor | NAD-dependent deacetylase sirtuin-6, UNKNOWN ATOM OR ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | sirt6, adp ribose, structural genomics, structural genomics consortium, sgc, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm : Q8N6T7 |
Total number of polymer chains | 6 |
Total formula weight | 240598.04 |
Authors | Pan, P.W.,Dong, A.,Qiu, W.,Loppnau, P.,Wang, J.,Ravichandran, M.,Bochkarev, A.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Min, J.,Edwards, A.M.,Structural Genomics Consortium (SGC) (deposition date: 2010-11-11, release date: 2011-01-26, Last modification date: 2023-09-06) |
Primary citation | Pan, P.W.,Feldman, J.L.,Devries, M.K.,Dong, A.,Edwards, A.M.,Denu, J.M. Structure and biochemical functions of SIRT6. J.Biol.Chem., 286:14575-14587, 2011 Cited by PubMed: 21362626DOI: 10.1074/jbc.M111.218990 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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