3PKC

M. tuberculosis MetAP with bengamide analog Y08, in Mn form

3PKC の概要

関連するPDBエントリー3IU7 3IU8 3IU9 3PKA 3PKB 3PKE 3PKD
分子名称Methionine aminopeptidase, MANGANESE (II) ION, (E,2R,3R,4S,5R)-N-[[(3S)-1-cyclopropylcarbonylpiperidin-3-yl]methyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, ... (4 entities in total)
機能のキーワードhydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
由来する生物種Mycobacterium tuberculosis
ポリマー鎖数1
分子量合計31458.32
構造登録者
Ye, Q.Z.,Lu, J.P. (登録日: 2010-11-11, 公開日: 2011-04-20, 最終更新日: 2017-11-08)
主引用文献
Lu, J.P.,Yuan, X.H.,Yuan, H.,Wang, W.L.,Wan, B.,Franzblau, S.G.,Ye, Q.Z.
Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6:1041-1048, 2011
PubMed: 21465667 (主引用文献が同じPDBエントリー)
DOI: 10.1002/cmdc.201100003
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.47 Å)
?

構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.214300.4%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード