3PHA

The crystal structure of the W169Y mutant of alpha-glucosidase (gh31 family) from Ruminococcus obeum atcc 29174 in complex with acarbose

Replaces:  3NXM

Summary for 3PHA

• Entry DOI: 10.2210/pdb3pha/pdb
• Related: 3NXM
• Related PRD ID: PRD_900007
• Descriptor: alpha-glucosidase, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (3 entities in total)
• Functional Keywords: structural genomics, psi-2, protein structure initiative, structuralcomplex, mcsg, midwest center for structural genomics, hydrolase, (beta/alpha)8-barrel, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Blautia obeum ATCC 29174
• Total number of polymer chains: 4
• Total formula weight: 312288.14

Authors

Tan, K.,Tesar, C.,Keigher, L.,Babnigg, G.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2010-11-03, release date: 2010-11-24, Last modification date: 2023-09-06)

• Primary citation: Tan, K.,Tesar, C.,Keigher, L.,Babnigg, G.,Joachimiak, A.; The crystal structure of the W169Y mutant of alpha-glucosidase (gh31 family) from Ruminococcus obeum atcc 29174 in complex with acarbose; To be Published,

Experimental method

X-RAY DIFFRACTION (2.173 Å)