3PH7

Crystal structure of Plasmodium vivax putative polyprenyl pyrophosphate synthase in complex with geranylgeranyl diphosphate

Replaces:  3MYS

Summary for 3PH7

• Entry DOI: 10.2210/pdb3ph7/pdb
• Related: 3LDW
• Descriptor: Farnesyl pyrophosphate synthase, GERANYLGERANYL DIPHOSPHATE (3 entities in total)
• Functional Keywords: malaria, farnesyl pyrophosphate synthase diphosphate, lyase, structural genomics, structural genomics consortium, sgc
• Biological source: Plasmodium vivax
• Total number of polymer chains: 4
• Total formula weight: 186664.77

Authors

Wernimont, A.K.,Dunford, J.,Lew, J.,Zhao, Y.,Kozieradzki, I.,Cossar, D.,Schapiro, M.,Bochkarev, A.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Hui, R.,Artz, J.D.,Structural Genomics Consortium (SGC) (deposition date: 2010-11-03, release date: 2010-11-17, Last modification date: 2024-02-21)

• Primary citation: Artz, J.D.,Wernimont, A.K.,Dunford, J.E.,Schapira, M.,Dong, A.,Zhao, Y.,Lew, J.,Russell, R.G.,Ebetino, F.H.,Oppermann, U.,Hui, R.; Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.; J.Biol.Chem., 286:3315-3322, 2011; PubMed: 21084289; DOI: 10.1074/jbc.M109.027235

Experimental method

X-RAY DIFFRACTION (2.5 Å)