3PH7

Crystal structure of Plasmodium vivax putative polyprenyl pyrophosphate synthase in complex with geranylgeranyl diphosphate

Replaces:  3MYS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Farnesyl pyrophosphate synthase	polymer	396	46215.8	4	UniProt (A5K4U6) Pfam (PF00348) In PDB	Plasmodium vivax
2	A, B, C, D	GERANYLGERANYL DIPHOSPHATE	non-polymer		450.4	4	Chemie (GRG)
3		water	water		18.0	92	Chemie (HOH)

Sequence modifications

A, B, C, D: 22 - 396 (UniProt: A5K4U6)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Arg 14	-	expression tag
Glu 15	-	expression tag
Asn 16	-	expression tag
Leu 17	-	expression tag
Tyr 18	-	expression tag
Phe 19	-	expression tag
Gln 20	-	expression tag
Gly 21	-	expression tag
Met 134	Thr 113	conflict
Asp 227	Asn 206	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	184863.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1801.8
All*	Total formula weight	186664.8

*Water molecules are not included.