3PDS
Irreversible Agonist-Beta2 Adrenoceptor Complex
Summary for 3PDS
Entry DOI | 10.2210/pdb3pds/pdb |
Related | 2RH1 |
Descriptor | Fusion protein Beta-2 adrenergic receptor/Lysozyme, 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, ... (4 entities in total) |
Functional Keywords | gpcr, signaling, beta adrenergic agonist, fusion protein, membrane protein-hydrolase complex, membrane protein/hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Multi- pass membrane protein : P07550 |
Total number of polymer chains | 1 |
Total formula weight | 53860.85 |
Authors | Rosenbaum, D.M.,Zhang, C.,Lyons, J.A.,Holl, R.,Aragao, D.,Arlow, D.H.,Rasmussen, S.G.F.,Choi, H.-J.,DeVree, B.T.,Sunahara, R.K.,Chae, P.S.,Gellman, S.H.,Dror, R.O.,Shaw, D.E.,Weis, W.I.,Caffrey, M.,Gmeiner, P.,Kobilka, B.K. (deposition date: 2010-10-24, release date: 2011-01-12, Last modification date: 2023-09-20) |
Primary citation | Rosenbaum, D.M.,Zhang, C.,Lyons, J.A.,Holl, R.,Aragao, D.,Arlow, D.H.,Rasmussen, S.G.F.,Choi, H.J.,Devree, B.T.,Sunahara, R.K.,Chae, P.S.,Gellman, S.H.,Dror, R.O.,Shaw, D.E.,Weis, W.I.,Caffrey, M.,Gmeiner, P.,Kobilka, B.K. Structure and function of an irreversible agonist-beta(2) adrenoceptor complex Nature, 469:236-240, 2011 Cited by PubMed: 21228876DOI: 10.1038/nature09665 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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