3PDS
Irreversible Agonist-Beta2 Adrenoceptor Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Fusion protein Beta-2 adrenergic receptor/Lysozyme | polymer | 458 | 52453.3 | 1 | UniProt (P07550) UniProt (P00720) Pfam (PF00001) Pfam (PF00959) In PDB | Homo sapiens (human) | Beta-2 adrenoreceptor, Beta-2 adrenoceptor |
2 | A | 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one | non-polymer | 444.5 | 1 | Chemie (ERC) | Endolysin, Lysis protein, Muramidase | ||
3 | A | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | Beta-2 adrenoreceptor, Beta-2 adrenoceptor | ||
4 | A | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) |
Sequence modifications
A: 25 - 230 (UniProt: P07550)
A: 1002 - 263 (UniProt: P00720)
A: 264 - 348 (UniProt: P07550)
PDB | External Database | Details |
---|---|---|
Gln 27 | Glu 27 | conflict |
Cys 93 | His 93 | engineered mutation |
Glu 187 | Asn 187 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 1054 | Cys 54 | engineered mutation |
Ala 1097 | Cys 97 | conflict |
PDB | External Database | Details |
---|---|---|
His 349 | - | expression tag |
His 350 | - | expression tag |
His 351 | - | expression tag |
His 352 | - | expression tag |
His 353 | - | expression tag |
His 354 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 52453.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1407.6 | |
All* | Total formula weight | 53860.8 |