3PD9

X-ray structure of the ligand-binding core of GluA2 in complex with (R)-5-HPCA at 2.1 A resolution

3PD9 の概要

• エントリーDOI: 10.2210/pdb3pd9/pdb
• 関連するPDBエントリー: 1NNP 3PD8
• 分子名称: Glutamate receptor 2, (5R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: ionotropic glutamate receptor glua2, ligand-binding core, agonist complex, membrane protein
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59367.79

構造登録者

Frydenvang, K.,Kastrup, J.S. (登録日: 2010-10-22, 公開日: 2010-12-29, 最終更新日: 2023-09-06)

• 主引用文献: Frydenvang, K.,Pickering, D.S.,Greenwood, J.R.,Krogsgaard-Larsen, N.,Brehm, L.,Nielsen, B.,Vogensen, S.B.,Hald, H.,Kastrup, J.S.,Krogsgaard-Larsen, P.,Clausen, R.P.; Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid.; J. Med. Chem., 53:8354-8361, 2010; PubMed: 21067182; DOI: 10.1021/jm101218a

実験手法

X-RAY DIFFRACTION (2.1 Å)