Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
A | 0016020 | cellular_component | membrane |
B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE HA5 A 260 |
Chain | Residue |
A | TYR58 |
A | MET193 |
A | HOH343 |
A | PRO86 |
A | LEU87 |
A | THR88 |
A | ARG93 |
A | GLY138 |
A | SER139 |
A | THR140 |
A | GLU190 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 261 |
Chain | Residue |
A | ARG28 |
A | HOH278 |
A | HOH333 |
A | HOH431 |
B | LYS180 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 262 |
Chain | Residue |
A | ARG145 |
A | TRP156 |
A | ARG160 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 263 |
Chain | Residue |
A | ARG28 |
A | LYS49 |
A | HOH378 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 264 |
Chain | Residue |
A | LYS113 |
A | LYS182 |
A | HOH322 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 265 |
Chain | Residue |
A | VAL96 |
A | GLY115 |
A | HOH370 |
site_id | AC7 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL A 266 |
site_id | AC8 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL A 267 |
Chain | Residue |
A | HIS43 |
A | GLN241 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 268 |
Chain | Residue |
A | ASP136 |
A | LYS141 |
A | HOH476 |
site_id | BC1 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE HA5 B 260 |
Chain | Residue |
B | TYR58 |
B | PRO86 |
B | LEU87 |
B | THR88 |
B | ARG93 |
B | GLY138 |
B | SER139 |
B | THR140 |
B | GLU190 |
B | MET193 |
B | HOH277 |
B | HOH288 |
site_id | BC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 261 |
Chain | Residue |
B | TRP156 |
B | ARG160 |
B | HOH275 |
site_id | BC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL B 262 |
Chain | Residue |
B | ALA60 |
B | ASP136 |
B | SER137 |
B | GLY138 |
B | LYS141 |
B | GLU142 |
B | ARG145 |
B | HOH388 |
site_id | BC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL B 263 |
Chain | Residue |
A | PRO102 |
A | LEU236 |
A | ASN239 |
B | ILE89 |
B | PRO102 |
B | LYS215 |
B | GLY216 |
site_id | BC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL B 264 |
Chain | Residue |
B | VAL96 |
B | GLY115 |
B | PRO117 |
B | HOH471 |
site_id | BC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 265 |
Chain | Residue |
B | HIS43 |
B | LYS237 |
B | GLN241 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | PRO86 | |
B | SER139 | |
B | THR140 | |
B | GLU190 | |
A | THR88 | |
A | ARG93 | |
A | SER139 | |
A | THR140 | |
A | GLU190 | |
B | PRO86 | |
B | THR88 | |
B | ARG93 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
Chain | Residue | Details |
A | ARG61 | |
A | ARG145 | |
A | LYS237 | |
B | ARG61 | |
B | ARG145 | |
B | LYS237 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
Chain | Residue | Details |
A | ILE118 | |
B | ILE118 | |
Chain | Residue | Details |
A | SER147 | |
B | SER147 | |
Chain | Residue | Details |
A | SER181 | |
B | SER181 | |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN0 | |
B | ASN0 | |