3PD9
X-ray structure of the ligand-binding core of GluA2 in complex with (R)-5-HPCA at 2.1 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glutamate receptor 2 | polymer | 260 | 29006.5 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (brown rat rat rats) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
| 2 | A, B | (5R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid | non-polymer | 184.1 | 2 | Chemie (HA5) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 114 (UniProt: P19491)
A, B: 117 - 259 (UniProt: P19491)
A, B: 117 - 259 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 115 | - | linker |
| Thr 116 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58013.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1354.8 | |
| All* | Total formula weight | 59367.8 |
