3PBR
Crystal structure of PBP3 complexed with meropenem
Summary for 3PBR
Entry DOI | 10.2210/pdb3pbr/pdb |
Related | 3PBN 3PBO 3PBQ 3PBS 3PBT |
Descriptor | Penicillin-binding protein 3, (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid (3 entities in total) |
Functional Keywords | pbp3, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 58714.93 |
Authors | |
Primary citation | Han, S.,Zaniewski, R.P.,Marr, E.S.,Lacey, B.M.,Tomaras, A.P.,Evdokimov, A.,Miller, J.R.,Shanmugasundaram, V. Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa. Proc.Natl.Acad.Sci.USA, 107:22002-22007, 2010 Cited by PubMed: 21135211DOI: 10.1073/pnas.1013092107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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