3PBT
Crystal structure of PBP3 complexed with MC-1
Summary for 3PBT
Entry DOI | 10.2210/pdb3pbt/pdb |
Related | 3PBN 3PBO 3PBQ 3PBR 3PBS |
Descriptor | Penicillin-binding protein 3, (4S,7Z)-7-(2-amino-1,3-thiazol-4-yl)-1-[({4-[(2R)-2,3-dihydroxypropyl]-3-(4,5-dihydroxypyridin-2-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}sulfonyl)amino]-4-formyl-10,10-dimethyl-1,6-dioxo-9-oxa-2,5,8-triazaundec-7-en-11-oate (3 entities in total) |
Functional Keywords | pbp3, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 59045.10 |
Authors | Han, S.,Evdokimov, A. (deposition date: 2010-10-20, release date: 2010-12-22, Last modification date: 2012-02-08) |
Primary citation | Han, S.,Zaniewski, R.P.,Marr, E.S.,Lacey, B.M.,Tomaras, A.P.,Evdokimov, A.,Miller, J.R.,Shanmugasundaram, V. Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa. Proc.Natl.Acad.Sci.USA, 107:22002-22007, 2010 Cited by PubMed: 21135211DOI: 10.1073/pnas.1013092107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.641 Å) |
Structure validation
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