3PAG

Crystal structure of the V130D mutant of OXA-24/40 in complex with doripenem

Summary for 3PAG

Entry DOI	10.2210/pdb3pag/pdb
Related	3ISG 3PAE
Descriptor	Beta-lactamase, (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	hydrolase, carbapenemase, hydrolase-antibiotic complex, hydrolase/antibiotic
Biological source	Acinetobacter baumannii
Total number of polymer chains	2
Total formula weight	56803.04
Authors	Powers, R.A.,Leonard, D.A.,Schneider, K.D. (deposition date: 2010-10-19, release date: 2011-01-19, Last modification date: 2023-09-06)
Primary citation	Schneider, K.D.,Ortega, C.J.,Renck, N.A.,Bonomo, R.A.,Powers, R.A.,Leonard, D.A. Structures of the Class D Carbapenemase OXA-24 from Acinetobacter baumannii in Complex with Doripenem. J.Mol.Biol., 406:583-594, 2011 Cited by PubMed: 21215758 DOI: 10.1016/j.jmb.2010.12.042 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation