3P8X
Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1alpha,25-Dihydroxyvitamin D3 with Substituents at C-18
Summary for 3P8X
Entry DOI | 10.2210/pdb3p8x/pdb |
Related | 1DB1 |
Descriptor | Vitamin D3 receptor, (1R,3S,5Z)-5-{(2E)-2-[(3aR,7aS)-7a-(7-hydroxy-7-methyloctyl)octahydro-4H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol, SULFATE ION, ... (4 entities in total) |
Functional Keywords | helices sandwich, transcription regulation, vitamin d, transcription regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P11473 |
Total number of polymer chains | 1 |
Total formula weight | 32303.18 |
Authors | Rochel, N.,Sato, Y.,Moras, D. (deposition date: 2010-10-15, release date: 2011-08-31, Last modification date: 2024-02-21) |
Primary citation | Verlinden, L.,Verstuyf, A.,Eelen, G.,Bouillon, R.,Ordonez-Moran, P.,Larriba, M.J.,Munoz, A.,Rochel, N.,Sato, Y.,Moras, D.,Maestro, M.,Seoane, S.,Dominguez, F.,Eduardo-Canosa, S.,Nicoletti, D.,Moman, E.,Mourino, A. Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1 ,25-Dihydroxyvitamin D3 with Substituents at C-18 Chemmedchem, 6:788-793, 2011 Cited by PubMed: 21520419DOI: 10.1002/cmdc.201100021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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