3OTX

Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Inhibitor AP5A

Summary for 3OTX

Entry DOI	10.2210/pdb3otx/pdb
Related	2XTB
Descriptor	Adenosine kinase, putative, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, SODIUM ION, ... (4 entities in total)
Functional Keywords	adenosine kinase, ap5a, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Trypanosoma brucei
Total number of polymer chains	2
Total formula weight	78141.67
Authors	Kuettel, S.,Greenwald, J.,Kostrewa, D.,Ahmed, S.,Scapozza, L.,Perozzo, R. (deposition date: 2010-09-14, release date: 2011-06-29, Last modification date: 2023-11-01)
Primary citation	Kuettel, S.,Greenwald, J.,Kostrewa, D.,Ahmed, S.,Scapozza, L.,Perozzo, R. Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation Plos Negl Trop Dis, 5:e1164-e1164, 2011 Cited by PubMed: 21629723 DOI: 10.1371/journal.pntd.0001164 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation